Parallel Tree Search-based Protein Conformation Analysis System

Makoto Ando, Yutaka Akiyama, Kentaro Onizuka, Tamotsu Noguchi

We have developed the Parallel Protein Conformation Analysis System, based on our implementation techniques used in parallel tree search programs. We employed an exhaustive search method for conformation search, rotating all the rotatable bonds by specified grain. We have implemented the system, and succeeded in analyzing the conformations of 20 amino acids individually. The parallel version of our program showed good speedups over the sequential version. We also succeeded in overlapping task management operations onto tree search operations by assigning them to multiple processes. We are aiming at analyzing the conformations of several amino acids that is useful in drug design.
Real World Computing Partnership