「寄付講座 臨床遺伝学研究室」の研究業績のデータです。 [ 論　文 ] 1. Sugawara K., Tajima Y., Kawashima I., Tsukimura T., Saito S., Ohno K., Iwamoto K., Kobayashi T., Itoh K., Sakuraba H.: Molecular interaction of imino sugars with human α-galactosidase: insight into the mechanism of complex formation and pharmacological chaperone action in Fabry disease. Mol. Genet. Metab., 96: 233-238, 2009. 2. Uemura T., Shiozaki K., Yamaguchi K., Miyazaki S., Satomi S., Kato K., Sakuraba H., Miyagi Y.: Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta4. Oncogene, 28: 1218-1229, 2009. 3. Sugawara K., Saito S., Sekijima M., Ohno K., Tajima Y., Kroos M.A., Reuser A.J.J., Sakuraba H.: Structural modeling of mutant α-glucosidases resulting in a processing/transport defect in Pompe disease. J. Hum. Genet., 54: 324-330, 2009. 4. Akeboshi H., Kasahara Y., Tsuji D., Itoh K., Sakuraba H., Chiba Y., Jigami Y.: Production of human β-hexosaminidase A with highly phosphorylated N-glycans by the overexpression of Ogataea minuta MNN4 gene. Glycobiology, 19: 1002-1009, 2009. 5. Morita M., Saito S., Ikeda K., Ohno K., Sugawara K., Suzuki T., Togawa T., Sakuraba H.: Structural basis of GM1 gangliosidosis and Morquio B disease. J. Hum. Genet., 54: 510-515, 2009. 6. Tajima Y., Kawashima I., Tsukimura T., Sugawara K., Kuroda M., Suzuki T., Togawa T., Chiba Y., Jigami Y., Ohno K., Fukushige T., Kanekura T., Itoh K., Ohashi T., Sakuraba H.: Use of a modified α-N-acetylgalactosaminidase in the development of enzyme replacement therapy for Fabry disease. Am. J. Hum. Genet., 85: 569-580, 2009.